Chih-Shung Wong Selected Research

Glutamic Acid (Glutamate)

4/2016	Sulfasalazine attenuates ACL transection and medial menisectomy-induced cartilage destruction by inhibition of cystine/glutamate antiporter.
10/2014	Rosiglitazone attenuates cerebral vasospasm and provides neuroprotection in an experimental rat model of subarachnoid hemorrhage.
12/2013	Intrathecal ultra-low dose naloxone enhances the antihyperalgesic effects of morphine and attenuates tumor necrosis factor-α and tumor necrosis factor-α receptor 1 expression in the dorsal horn of rats with partial sciatic nerve transection.
10/2013	Attenuation of neurological injury with early baicalein treatment following subarachnoid hemorrhage in rats.
5/2013	Intrathecal glutamate release during hindlimb tourniquet inflation and femoral artery occlusion in rats.
12/2011	Intrathecal ultra-low dose naloxone enhances the antinociceptive effect of morphine by enhancing the reuptake of excitatory amino acids from the synaptic cleft in the spinal cord of partial sciatic nerve-transected rats.
3/2011	Temporal changes in glutamate, glutamate transporters, basilar arteries wall thickness, and neuronal variability in an experimental rat model of subarachnoid hemorrhage.
3/2010	Intramuscular bupivacaine injection dose-dependently increases glutamate release and muscle injury in rats.
8/2009	N-Methyl-D-aspartate receptor antagonist d-AP5 prevents pertussis toxin-induced alterations in rat spinal cords by inhibiting increase in concentrations of spinal CSF excitatory amino acids and downregulation of glutamate transporters.
10/2008	Ultra-low-dose naloxone restores the antinociceptive effect of morphine and suppresses spinal neuroinflammation in PTX-treated rats.

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Chih-Shung Wong Research Topics

Disease

40	Pain (Aches) 09/2023 - 06/2002
23	Hyperalgesia 09/2021 - 02/2003
16	Neuralgia (Stump Neuralgia) 07/2023 - 12/2003
15	Postoperative Pain 09/2023 - 11/2003
12	Neuroinflammatory Diseases 06/2016 - 09/2006
7	Knee Osteoarthritis 04/2023 - 01/2013
7	Neoplasms (Cancer) 12/2021 - 06/2002
7	Osteoarthritis 12/2021 - 05/2005
6	Inflammation (Inflammations) 04/2023 - 07/2003
5	Body Weight (Weight, Body) 12/2021 - 12/2005
5	Cough 09/2016 - 09/2005
4	Postoperative Nausea and Vomiting (PONV) 12/2022 - 10/2010
4	Hypotension (Low Blood Pressure) 12/2021 - 12/2004
4	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 10/2014 - 03/2011
4	Intracranial Vasospasm 10/2014 - 12/2004
4	Heart Arrest (Cardiac Arrest) 03/2008 - 10/2002
3	Vomiting 01/2021 - 03/2002
3	Nausea 01/2021 - 03/2002
3	Hypoxia (Hypoxemia) 01/2017 - 06/2004
3	Sepsis (Septicemia) 09/2005 - 02/2003
2	Respiratory Insufficiency (Respiratory Failure) 01/2021 - 01/2018
2	Chronic Pain 08/2020 - 06/2006
2	Shoulder Pain 08/2016 - 07/2008
2	Brain Injuries (Brain Injury) 10/2013 - 08/2003
2	Hemorrhage 10/2013 - 03/2011
2	Ischemia 05/2013 - 12/2004
2	Back Pain (Backache) 11/2009 - 06/2005
2	Shock 06/2007 - 03/2002

Drug/Important Bio-Agent (IBA)

35	Morphine (MS Contin)FDA LinkGeneric 07/2023 - 06/2002
18	Analgesics (Analgesic Drugs)IBA 06/2022 - 06/2002
16	Opioid Analgesics (Opioids)IBA 09/2023 - 06/2002
14	Glutamic Acid (Glutamate)FDA Link 04/2016 - 06/2002
10	CytokinesIBA 04/2023 - 12/2003
9	Fentanyl (Sublimaze)FDA LinkGeneric 06/2022 - 03/2002
9	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 03/2017 - 02/2003
9	Excitatory Amino AcidsIBA 04/2016 - 06/2002
8	Anesthetics (Anesthetic Agents)IBA 01/2022 - 09/2002
8	Naloxone (Narcan)FDA LinkGeneric 09/2016 - 10/2008
7	Propofol (Diprivan)FDA LinkGeneric 12/2021 - 12/2016
6	Lidocaine (Xylocaine)FDA LinkGeneric 01/2017 - 06/2002
6	Dialysis SolutionsIBA 12/2011 - 12/2003
5	Desflurane (I 653)FDA Link 03/2019 - 10/2010
5	N-Methylaspartate (NMDA)IBA 09/2011 - 02/2003
5	Pertussis ToxinIBA 08/2009 - 02/2003
4	MelatoninIBA 01/2022 - 05/2016
4	Nitric Oxide (Nitrogen Monoxide)FDA Link 07/2017 - 12/2003
4	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 07/2017 - 07/2004
4	Dextromethorphan (Racemethorphan)FDA LinkGeneric 03/2017 - 06/2004
4	Ropivacaine (Naropin)FDA LinkGeneric 01/2017 - 03/2002
4	Bupivacaine (Bupivacaine Hydrochloride)FDA LinkGeneric 01/2017 - 02/2003
4	Ketamine FDA LinkGeneric 09/2016 - 02/2003
4	Aspartic Acid (Aspartate)FDA Link 10/2008 - 06/2002
4	KetorolacIBA 07/2008 - 03/2002
3	Interleukin-6 (Interleukin 6)IBA 11/2018 - 11/2004
3	p38 Mitogen-Activated Protein KinasesIBA 07/2017 - 08/2005
3	Local AnestheticsIBA 01/2017 - 06/2006
3	SolutionsIBA 12/2016 - 06/2002
3	Hyaluronic Acid (Hyaluronan)IBA 04/2016 - 05/2006
3	CarrageenanIBA 08/2014 - 12/2003
3	Interleukin-10 (Interleukin 10)IBA 09/2012 - 12/2003
3	Meperidine (Pethidine)FDA LinkGeneric 07/2008 - 06/2004
3	Interleukin-1beta (Interleukin 1 beta)IBA 06/2007 - 07/2004
3	Clonidine (ST 155)FDA LinkGeneric 05/2007 - 08/2004
3	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 11/2005 - 07/2003
2	SugammadexIBA 12/2022 - 10/2022
2	Neostigmine (Neostigmine Bromide)IBA 12/2022 - 10/2022
2	Rocuronium (Zemuron)FDA LinkGeneric 10/2022 - 12/2012
2	Tramadol (K315)FDA LinkGeneric 06/2022 - 03/2019
2	TriterpenesIBA 01/2019 - 01/2016
2	baicaleinIBA 11/2018 - 10/2013
2	ResveratrolIBA 06/2016 - 10/2012
2	Type I Tumor Necrosis Factor ReceptorsIBA 06/2016 - 12/2013
2	baicalinIBA 08/2014 - 12/2003
2	Indicators and Reagents (Reagents)IBA 01/2014 - 06/2006
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2012 - 11/2004
2	Etanercept (Enbrel)FDA Link 07/2011 - 02/2011
2	Protein Isoforms (Isoforms)IBA 08/2009 - 02/2003
2	Amitriptyline (Elavil)FDA LinkGeneric 06/2009 - 09/2006

Therapy/Procedure

17	Anesthesia 09/2023 - 03/2002
14	Therapeutics 09/2023 - 07/2003
13	Analgesia 09/2023 - 03/2002
6	Pain Management 09/2023 - 06/2006
5	General Anesthesia 10/2022 - 09/2003
5	Catheters 09/2021 - 08/2002
4	Intravenous Anesthesia 03/2019 - 03/2017
4	Spinal Anesthesia 11/2009 - 06/2005
3	Patient-Controlled Analgesia (Analgesia, Patient Controlled) 03/2019 - 11/2004
3	Epidural Analgesia 09/2016 - 05/2005
3	Spinal Injections 08/2014 - 02/2003
3	Acupressure (Shiatsu) 01/2010 - 07/2008
3	Punctures 03/2007 - 03/2005
2	Meniscectomy 09/2021 - 01/2019
2	Laparoscopic Cholecystectomy 01/2020 - 07/2008
2	Knee Replacement Arthroplasty (Total Knee Replacement) 01/2017 - 05/2007
2	Intravenous Injections 01/2017 - 02/2007
2	Operative Surgical Procedures 01/2017 - 08/2004
2	Tourniquets 05/2013 - 06/2002
2	Aftercare (After-Treatment) 01/2010 - 03/2007
2	Bed Rest (Bedrest) 11/2009 - 11/2006
2	Resuscitation 06/2007 - 08/2003